MALIGNANT TRIGEMINAL NERVE SHEATH TUMOR AND ANAPLASTIC ASTROCYTOMA COLLISION TUMOR WITH HIGH PROLIFERATIVE ACTIVITY AND TUMOR SUPPRESSOR P53 EXPRESSION

Background.The synchronous development of two primary brain tumors of distinct cell of origin in close proximity or in contact with each other is extremely rare.We present the first case of collision tumor with two histological distinct tumors.Case Presentation.A 54-year-old woman presented with progressive atypical left facial pain and numbness fo

At the same time that COVID-19 cases in the United States first began to increase, fellows in a mentored teaching apprenticeship for postdoctoral scientists began to teach undergraduate seminars.The fellows suddenly needed to support students emotionally and switch to online instruction.They were encouraged to acknowledge and address the pandemic d

Laforin and Malin are two proteins that are encoded by the genes EPM2A and EPM2B, respectively.Laforin is a glucan phosphatase and Malin is an E3-ubiquitin ligase, Mops and these two proteins function as a complex.Mutations occurring at the level of one of the two genes lead to the accumulation of an aberrant form of glycogen meant to cluster in po